Infection with Herpes-Simplex Viruses 1 and 2

The Infected HostThe effects of HSV on the host can best be appreciated by analysis of both the epidemiologic and the clinicopathological aspects of the infection. In this way, the modes of spread and acquisition of the virus and its distribution in various body sites can be examined in relation to the clinical responses elicited in various kinds of hosts (newborns, immunologically compromised persons, etc.).Epidemiologic PatternsStudies in the "second" period of HSV research (around 1920 to about 1960) brought into relief three important points: that patients experiencing either initial or recurrent HSV infections often fail to have . . .