Answers are grounded in this paper and cite their sources.
Chemical synthesis study demonstrates rapid asymmetric transfer hydrogenation of propargyl ketones via a ruthenium catalyst, suggesting an efficient route to chiral acetylenic alcohols.
The asymmetric transfer hydrogenation of α,β‐propargyl ketones catalyzed by an in situ formed ruthenium–hydroxyamide complex was explored. The acetylenic alcohols were isolated in good to excellent yields with excellent ee values (typically >90 %) after short reaction times at room temperature.
No takes yet. Share an insight, caveat, or question.
Shatskiy et al. (2015) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: