The effects ofpulmonary hypertension on cardiopulmonary function were investigated by ventilatory, haemo- dynamic, and metabolic studies at rest and during exercise. The studies were carried out in 12 patients with primary, thromboembolic, or residual pulmonary hypertension after surgical closure of intracardiac defects, and in II patients with pulmonary hypertension secondary to obstructive lung disease. The findings have been compared with earlier published results of similar studies, performed in other situations associated with pul- monary hypertension.
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Gazetopoulos et al. (1974) studied this question.
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