Two strains of Acinetobacteria have been studied in order to perform enantioselective Baeyer-Villiger-type oxidations of racemic alpha-substituted cyclopentanones. This allows a one-step synthesis of various delta-lactones showing optical purities up to 97%, using whole-cell procedures. Tetraethylpyrophosphate and 1,2-cyclohexanediol have been used in order to enhance the yields of the bioconversion. The obtained (S)-lactones are of high interest as readily accessible chirons as well as to the flavor industry.
No takes yet. Share an insight, caveat, or question.
Alphand et al. (1990) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: