Synthesis and Insecticidal Evaluation of Novel N‐pyridylpyrazole Derivatives Containing Diacylhydrazine/1,3,4‐Oxadiazole Moieties

Two series of novel N ‐pyridylpyrazole derivatives containing diacylhydrazine/1,3,4‐oxadiazole moieties were designed and synthesized based on the structure of chlorantraniliprole and characterized via 1 H‐NMR, 13 C‐NMR, IR, MS, and elemental analysis. The preliminary bioassay indicated that some of the title compounds I and II exhibited larvicidal activities against Mythimna separata with 90–100% death rates at 500 mg/L. The further test showed that these compounds had weak insecticidal activity against Mythimna separata and Plutella xylostella at 200 mg/L and might be not suitable as insecticide lead compound for further optimization.