Unbending: Asymmetric pulsed field electrophoresis of DNA was conducted in a nanoporous array formed by colloidal self-assembly of nanoparticles inside a microfluidic system. In confinement smaller than the persistence length of DNA molecules, DNA is maintained in highly stretched conformation. A model correlating pulse frequency, electric field, and molecular size with the observed angular dispersion was developed and experimentally verified.
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Nazemifard et al. (2010) studied this question.
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