Why the study?
Does plasma exchange improve symptoms in a patient with severe insulin-resistant diabetes and autoantibodies to the insulin receptor?
Does plasma exchange improve symptoms in a patient with severe insulin-resistant diabetes and autoantibodies to the insulin receptor?
This case report describes the use of plasma exchange for a patient with severe insulin resistance due to insulin receptor autoantibodies.
Plasma exchange in insulin receptor autoantibody-mediated resistance remains hypothesis-generating; prospective studies are needed before clinical adoption.
WE recently described two groups of patients with severe insulin-resistant diabetes and acanthosis nigricans.1 In these patients the defect of insulin action could be correlated with markedly abnor...
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Muggeo et al. (1979) studied this question.
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