Recurrent haemophilus septicaemia and immunoglobulin deficiency.

Infection with Haemophilus influenzae type b is often subclinical but may give rise to septicaemic illnesses One infection appears to give long-lasting immunity (Fothergill and Wright, 1933). Hypo-y-globulinaemia or splen- ectomy can predispose to a single attack of haemo- philus meningitis, or to repeated respiratory infections due to non-capsulated organisms. Recurrent pneumococcal septicaemia has often been described in immune-deficiency syndromes, but in a survey of the published papers no report of a second episode of haemophilus septicaemia was found (Good et al., 1960; Eraklis et al., 1967).