The integration of autonomous transmissible plasmids into the chromosome ofEscherichia coliK12

SUMMARY The highly selective technique of integrative suppression has been used to determine the ability of autonomous transmissible plasmids to integrate into the E. coli chromosome. All the F -like transmissible plasmids appear to be able to integrate, suppress the initiation defect and form Hfr -type donor strains. However, there is no evidence of integration with the I -like transmissible plasmids examined.