Population
Primary bovine calf-kidney cell layers infected with foot-and-mouth disease virus
Comparison
Defined medium containing glucose as the only… vs Complex media containing serum and lactalbumin…
Design
Preclinical
Authors
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Simplifies FMDV propagation in bovine cells; leaves open translation to other viruses or in vivo models.
A defined medium with glucose and phosphate supports foot-and-mouth disease virus replication in bovine calf-kidney cells equivalently to complex media, facilitating short-term biochemical investigations.
Pledger et al. (1962) studied this question.
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