Sensitivity of the Normal and Denervated Parotid Gland to Chemical Agents

Summary. Experiments are described which show that parasympathetic denervation of the parotid gland renders the gland more sensitive to the secretory action of acetylcholine, adrenaline and pilocarpine. Postganglionic denervation induces a greater sensitization than preganglionie denervation as regards acetylcholine and pilocarpine. The reverse seems to be true for adrenaline. Some evidence is given to show that sympathetic stimulation arid injection of adrenaline has dual action on the parotid gland of the cat, apart from that on the vessels, one secretory and one expelling.