Highlights a severe complication of dextran-induced ARDS during intracoronary stenting that can occur even with hapten dextran 1 premedication.
Dextran-induced ARDS can occur despite hapten premedication; leaves open optimal prophylaxis during intracoronary procedures.
A case of dextran induced adult respiratory distress syndrome is used to illustrate the most serious complication of dextran usage during intracoronary stent placement. This reaction occurred despite premedication with the hapten dextran 1. Mechanisms of dextran induced complications are discussed. A mechanism for hapten resistant dextran reactions is postulated. Suggestions to prevent such reactions are made.
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Gossman et al. (1996) studied this question.
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