Population
Human umbilical vein endothelial cells from 3 normal subjects and 1 female child with von Willebrand's disease
Comparison
Cell culture and characterization vs Normal human umbilical vein endothelial cells
Design
Preclinical
Authors
Loading...
Endothelial vWF defects in vWD should not change practice; leaves open mechanistic studies of endothelial production as a therapeutic target.
Cultured endothelial cells from a patient with von Willebrand's disease demonstrate distinct morphological and functional differences, including reduced production of von Willebrand factor activity, compared to normal cells.
Booyse et al. (1981) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: