Case series reports variable clinical and radiological presentations of neurocysticercosis in rural individuals, highlighting the importance of diagnostic suspicion in non-endemic settings.
Neurocysticercosis can present a diagnostic challenge in settings where it is not routinely suspected. Although endemic in many developing regions, it remains uncommon in Morocco, which may delay diagnosis. We report three cases illustrating its clinical and radiological variability in a non-endemic setting. All patients came from rural areas and presented with seizures, while one also reported chronic headaches and severe fatigue. Neuroimaging revealed predominantly parenchymal lesions at different evolutionary phases, including scolex-containing lesions, calcifications, and a ring-enhancing lesion suggestive of the colloidal phase. Serology may provide supportive evidence, but a negative result does not exclude intraparenchymal neurocysticercosis. These cases emphasize the importance of considering neurocysticercosis in patients with suggestive neurological and radiological findings, even in non-endemic settings.
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Marbouh et al. (2026) studied this question.
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