A ruthenium‐catalyzed direct mono‐C−H functionalization/annulation cascade reaction of benzimidates and sulfoxonium ylides has been developed. The reaction proceeds smoothly with a broad range of substrates, giving access to a variety of isoquinoline derivatives in moderate to good yields using an organic acid additive under oxidant free conditions. magnified image
No takes yet. Share an insight, caveat, or question.
Shi et al. (2018) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: