The anthelmintic efficacy of four plants of the Cucurbitaceae against Hymenolepis nana (tapeworm) and Aspicularis tetraptera (pinworm) infections in mice was evaluated utilizing piperazine citrate as a reference substance for comparison. The ethanolic extracts of the seeds of Cucumis sativus, Cucurbita maxima and Lagenaria siceraria exhibited a potent activity against tapeworms which was comparable to the effect of piperazine citrate. Some activity against pinworms was demonstrated by seeds of Cucurbita maxima.
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Elisha et al. (1987) studied this question.
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