Why the study?
Are higher anti-Factor Xa levels associated with a reduced need for circuit/membrane oxygenator change due to thrombus formation in pediatric patients on ECMO?
Are higher anti-Factor Xa levels associated with a reduced need for circuit/membrane oxygenator change due to thrombus formation in pediatric patients on ECMO?
Higher anti-Factor Xa concentrations are associated with a decreased need for circuit or membrane oxygenator changes due to thrombosis in pediatric patients on ECMO.
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May support higher anti-FXa targets to reduce pediatric ECMO circuit changes; hypothesis-generating and requires prospective confirmation.
Irby et al. (2014) studied this question.
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