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April 18, 2017Science Signaling

The FOXM1 inhibitor RCM-1 suppresses goblet cell metaplasia and prevents IL-13 and STAT6 signaling in allergen-exposed mice

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Authors

LSLifeng SunShandong Provincial HospitalXRXiaomeng RenDalian Polytechnic UniversityIWI‐Ching WangUniversity of California, San Francisco

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Sun et al. (2017) studied this question.

synapsesocial.com/papers/6a857406d06b31cc19d0beb3https://doi.org/10.1126/scisignal.aai8583
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1β‐catenin and Kras/Foxm1 signaling pathway are critical to restrict Sox9 in basal cells during pulmonary branching morphogenesis2016 · 39 citations
  2. 2The genetics of asthma and allergic disease: a 21st century perspective2011 · 715 citations
  3. 3Blocking airway mucous cell metaplasia by inhibiting EGFR antiapoptosis and IL-13 transdifferentiation signals2006 · 269 citations
  4. 4Is there potential to target FOXM1 for ‘undruggable’ lung cancers?2015 · 19 citations