Key result
Tranexamic acid therapy successfully treated the re-expansion of a thrombosed false lumen after acute type B aortic dissection, leading to its complete disappearance at 3 months with no recurrence at 2 years.
Why the study?
Re-expansion of a thrombosed false lumen after aortic dissection due to collateral retrograde flow is rarely reported, and local surgical or endovascular management may be ineffective if retrograde flow recurs from another branch.
Does tranexamic acid therapy improve re-expansion of thrombosed false lumen after acute type B aortic dissection in a patient with collateral retrograde flow?
Case Report (n=1)
No
Does tranexamic acid therapy improve re-expansion of thrombosed false lumen after acute type B aortic dissection in a patient with collateral retrograde flow?
Tranexamic acid therapy may be an effective medical treatment for re-expansion of a thrombosed false lumen after aortic dissection due to collateral retrograde flow from aortic branches.
Supports potential role of tranexamic acid for false lumen resolution in type B dissection; hypothesis-generating, should not yet change practice.
Re-expansion of thrombosed false lumen after aortic dissection due to collateral retrograde flow from the aortic branches has rarely been reported. Surgical or endovascular local management such as ligation or occlusion of culprit arteries may not be effective in case retrograde blood flow to the false lumen might occur again from another branch after the operation. Here, we report a 68-year-old woman with re-expansion of the thrombosed false lumen after acute type B aortic dissection due to collateral retrograde flow from the aortic branches successfully treated with tranexamic acid therapy and antihypertensive therapy.
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Hamuro et al. (2021) conducted a case report in Re-expansion of thrombosed false lumen after acute type B aortic dissection (n=1). Tranexamic acid and antihypertensive therapy was evaluated on Regression and disappearance of the thrombosed false lumen. Tranexamic acid therapy successfully treated the re-expansion of a thrombosed false lumen after acute type B aortic dissection, leading to its complete disappearance at 3 months with no recurrence at 2 years.
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