What question did this study set out to answer?

Review the clinical progress and pathophysiological mechanisms underlying coronary artery disease and localized disorders in myocardial contraction.

Localized Disorders in Myocardial Contraction

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Encouraging CAD pathophysiology progress supports sustained research investment; leaves open clinical translation.

Review the clinical progress and pathophysiological mechanisms underlying coronary artery disease and localized disorders in myocardial contraction.
Narrative historical review synthesizing diagnostic and physiological advances in coronary artery disease.
Evaluation of the transition from postmortem morbid anatomy to in vivo physiological measurements using cardiac catheterization.
Application of cardiac catheterization has enabled dynamic assessment of coronary hemodynamics and myocardial metabolism.
Investigation into coronary heart disease has successfully expanded beyond descriptive structural pathology to focus on functional contraction abnormalities.

A 1967 study studied this question.

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