Why the study?
Does the complement fixation method improve the sensitivity of CRP estimation compared to the precipitin method in human serum?
Does the complement fixation method improve the sensitivity of CRP estimation compared to the precipitin method in human serum?
The complement fixation method provides a more sensitive and precise estimate of CRP levels in human serum compared to the precipitin method, potentially aiding in monitoring therapy efficacy.
A complement fixation method based on the reaction between CRP in human test sera and rabbit CRP antisera has been described. This technic provides a precise and reproducible estimate of the relative amounts of CRP in human serum. The procedure has greater sensitivity than the precipitin method and may be of greater value in following the efficacy of therapy.
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Muschel et al. (1954) studied this question.
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