Key result
Stress-guided balloon pulmonary valvuloplasty markedly improves stroke volume response and peak VO2 in pulmonary stenosis.
Why the study?
When resting gradients are near the lower boundary of moderate pulmonary valve stenosis, determining whether exercise intolerance is attributable to the stenosis can be challenging.
Does balloon pulmonary valvuloplasty improve stroke volume response and peak VO2 in a patient with moderate pulmonary valve stenosis and exercise intolerance?
Case Report (n=1)
Does balloon pulmonary valvuloplasty improve stroke volume response and peak VO2 in a patient with moderate pulmonary valve stenosis and exercise intolerance?
Exercise stress echocardiography and cardiopulmonary exercise testing can help guide treatment decisions for balloon pulmonary valvuloplasty in patients with symptomatic moderate pulmonary valve stenosis.
Exercise testing may clarify symptom attribution in borderline PVS; leaves open need for prospective validation before routine use.
Current guidelines recommend balloon pulmonary valvuloplasty (BPV) for symptomatic adults with moderate or severe pulmonary valve stenosis (PVS) when the valve anatomy is suitable. However, when the resting gradient is near the lower boundary of the moderate range, establishing whether exercise intolerance is attributable to PVS can be challenging. We describe the case of a 52‐year‐old woman with longstanding PVS who developed progressive exercise intolerance. Resting echocardiography revealed a peak gradient of 38 mmHg, which remained stable during follow‐up. Exercise stress echocardiography (ESE) demonstrated a blunted stroke volume response, whereas cardiopulmonary exercise testing (CPET) showed reduced peak VO 2 . Based on these objective findings, BPV was performed for symptomatic moderate PVS. Following successful intervention, both the stroke volume response and peak VO 2 improved markedly. This case highlights that exercise‐based diagnostic modalities, particularly ESE in conjunction with CPET, can help guide treatment decisions in symptomatic moderate PVS.
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Komaki et al. (2026) conducted a case report in Pulmonary Valve Stenosis (n=1). Balloon pulmonary valvuloplasty was evaluated on Stroke volume response and peak VO2. Balloon pulmonary valvuloplasty guided by exercise stress echocardiography and cardiopulmonary exercise testing markedly improved stroke volume response and peak VO2 in a patient with moderate pulmonary valve stenosis.
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