Why the study?
Does antibiotic prophylaxis prevent infection in patients undergoing cardiac surgery?
Does antibiotic prophylaxis prevent infection in patients undergoing cardiac surgery?
This review discusses the historical context and reawakening of interest in antibiotic prophylaxis for cardiac surgery.
Reawakening interest in prophylaxis for cardiac surgery warrants no practice change; leaves open need for updated RCTs.
Antibiotic prophylaxis and open-heart surgery have been associated almost from the beginnings of valve replacement.Enthusiastically adopted as a means of controlling and preventing infection of the prosthetic valve, the value of chemoprophylaxis was subsequently challenged.1,2Scientific respectability for antibiotic prophylaxis in other surgical dis- ciplines has led to a reawakening of interest.
No takes yet. Share an insight, caveat, or question.
Freeman et al. (1986) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: