Control of cross-infection in an intensive care unit

SUMMARY In a survey undertaken in an intensive care unit, coliform bacilli were found to be responsible for most infections, Pseudomonas aeruginosa and Staphylococcus aureus being isolated much less frequently. Tracheostomy or endotracheal intubation predisposed to infection, but in our experience intermittent positive pressure ventilation did not significantly affect its incidence. Little cross-infection has occurred, and it has never been possible to incriminate the ventilators in its transmission. We gratefully acknowledge the assistance we have received from colleagues in the Intensive Therapy Unit and the Department of Bacteriology during the course of this investigation.