Key result
Prolonged total ischemic time (≥180 minutes) in STEMI patients was significantly associated with a higher one-year composite rate of death, rehospitalization, and revascularization compared to shorter ischemic time (54.2% vs 23.3%).
Why the study?
Although a relationship between total ischemic time and clinical outcomes has been reported in STEMI patients undergoing PCI, this relationship remained to be clarified.
Does prolonged total ischemic time (≥180 minutes) increase the composite of death, rehospitalization, and revascularization in STEMI patients undergoing primary PCI?
Observational (n=113)
No
Does prolonged total ischemic time (≥180 minutes) increase the composite of death, rehospitalization, and revascularization in STEMI patients undergoing primary PCI?
In STEMI patients undergoing primary PCI, a total ischemic time of ≥180 minutes is associated with a significantly higher risk of the composite of death, rehospitalization, and revascularization at one year compared to <180 minutes.
A dedicated relationship between total ischemic time (TIT) and clinical outcomes has been reported in ST-elevation myocardial infarction (STEMI) patients undergoing percutaneous coronary intervention (PCI); however, this claim is yet to be clarified. Accordingly, this study was carried out to determine the association of TIT with in-hospital and one-year follow-up outcomes in STEMI patients undergoing primary PCI.
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Kurmi et al. (2022) conducted an observational in ST-Elevation Myocardial Infarction (STEMI) (n=113). Prolonged total ischemic time (≥180 minutes) vs. Shorter total ischemic time (<180 minutes) was evaluated on Composite of death, rehospitalization, and revascularization at one-year follow-up (p=0.007). Prolonged total ischemic time (≥180 minutes) in STEMI patients was significantly associated with a higher one-year composite rate of death, rehospitalization, and revascularization compared to shorter ischemic time (54.2% vs 23.3%).
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