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Polyketide synthases are the main biochemical machinery for the production of a structurally diverse group of natural products, polyketides. Their heterologous expression enables overproduction of target compounds, generation of novel analogs, and provides a basic understanding of their reaction programs. This Highlight outlines the current state of heterologous expression of type I, type II, and type III polyketide synthases of microbial and plant origins.
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Isao Fujii (2008) studied this question.
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