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January 1, 1992The Journal of AntibioticsOpen Access

C-13.BETA.-Acyloxymilbemycine, a new family of macrolides. Discovery, structural determination and hological properties.

MARK A. MAXELL B.F. Bishop PATRICIA BRYCE KENNETH A. F. ORATION HAMIDA KARA Robert A. Monday MICHAEL S. PACEY David A. Perry Yasuhiro Kojima Hiroshi Maeda Satoshi Nishiyama JUNSUKE TONE Liang Huang

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Abstract

A family of novel milbemycins possessing C-13 beta-acyloxy substitution was produced by Streptomyces hygroscopicus ATCC 53718. These compounds were detected by HPLC diode array analysis and possess anthelmintic and ectoparasiticidal activity. The origin of the oxygen atom at C-13 is discussed.

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MAXELL et al. (1992) studied this question.

synapsesocial.com/papers/6a859d89f047f857d83db79d https://doi.org/10.7164/antibiotics.45.659

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