Key result
Age, male sex, preceding cardiovascular disease, acute renal failure, acute respiratory failure, APACHE score, and vasopressor use were identified as strong risk factors for new-onset AF in the ICU.
Why the study?
The study was performed to systematically review available evidence on risk factors for new-onset atrial fibrillation on the general adult ICU and provide a semi-quantitative evidence synthesis.
What are the risk factors for new-onset atrial fibrillation in adults admitted to the general ICU?
Systematic Review (n=17)
What are the risk factors for new-onset atrial fibrillation in adults admitted to the general ICU?
Answers are grounded in this paper and cite their sources.
Age, male sex, preceding cardiovascular disease, acute renal failure, acute respiratory failure, APACHE score, and vasopressor use are strong risk factors for new-onset atrial fibrillation in the general adult ICU.
PURPOSE: This study was performed to systematically review the available evidence for the risk factors for new-onset atrial fibrillation (NOAF) on the general adult intensive care unit (ICU) and provide a semi-quantitative evidence synthesis. METHODS: We searched the MEDLINE, EMBASE, Cochrane Database of Systematic Reviews and the CENTRAL databases from 1970 to 2018. We included studies of adults based in general ICUs that evaluated potential risk factors for NOAF. We excluded studies involving patients with a history of atrial fibrillation (AF). We semi-qualitatively evaluated the strength of evidence for each identified variable. RESULTS: We screened 1447 studies. Seventeen studies were included in the final analysis. We identified strong evidence for age, male sex, preceding cardiovascular disease, acute renal failure, acute respiratory failure, APACHE score and the use of vasopressors as risk factors for the development of NOAF on the ICU. Modifiable risk factors had not been studied in detail. CONCLUSIONS: We provide the first systematic review with evidence synthesis of risk factors for NOAF on the general adult ICU. Evidence for modifiable risk factors was limited. Further research is therefore required and may contribute towards the evidence-based prevention and management of this important condition.
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Bedford et al. (2019) conducted a systematic review in New-onset atrial fibrillation (NOAF) (n=17). Risk factors (age, male sex, cardiovascular disease, acute renal/respiratory failure, APACHE score, vasopressors) was evaluated on Development of new-onset atrial fibrillation (NOAF). Age, male sex, preceding cardiovascular disease, acute renal failure, acute respiratory failure, APACHE score, and vasopressor use were identified as strong risk factors for new-onset AF in the ICU.
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