New-Onset Atrial Fibrillation in the Critically Ill*

Figures

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  Figure 1.. Flowchart of criteria for categorization of atrial fibrillation (AF) status. Flowchart of patient admissions analyzed and definitions of categorization according to AF status. ECG = electrocardiogram, MICU = medical ICU, SICU = surgical/trauma/burn ICU.

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  Figure 2.. Cumulative incidence of atrial fibrillation (AF). Cumulative incidence of AF as a function of time monitored. There was no significant difference in the cumulative incidence of AF as a function of time monitored between the groups with AF (p = 0.613).

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  Figure 3.. Determinants of atrial fibrillation, length of stay, and hospital mortality. Effect of each (A) categorical predictor or (B) continuous predictor across its range on the log odds of developing atrial fibrillation. ses represented by line height or ribbon width, respectively. Grayscale is the relative proportion of variance accounted for by each term measured by Wald chi-square statistics (χ2) minus the degrees of freedom (df). OASIS = Oxford Acute Severity of Illness Score.

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  Figure 4.. Determinants of ICU length of stay and hospital mortality. A, Estimated marginal effects on ICU length of stay of most significant predictors and atrial fibrillation (AF) status. For continuous predictors, we estimated the marginal effect between the interquartile range (75th percentile value vs 25th percentile value). B, Estimated odds ratio on hospital mortality of most significant predictors and AF status. For continuous predictors, we estimated the odds ratio between the interquartile range (75th percentile value vs 25th percentile value). OASIS = Oxford Acute Severity of Illness Score.

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  Figure 5.. Impact of new-onset atrial fibrillation (AF) on outcomes. A, Probability of survival after hospital discharge according to AF status. Survival estimates at time zero reflect the differences in hospital mortality where admissions with new-onset clinical AF had by the poorest hospital mortality. B, Fold change in hospital outcomes—ICU length of stay (ICU LOS) and hospital mortality for new-onset subclinical and clinical AF as a function of the median AF burden, quantified as the percentage of all ICU monitoring, compared to propensity-matched controls without any AF.