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In the course of testing the possible coenzymic function of the phosphorylated vitamin B, derivatives on the synthesis of glucosamine 6-phosphate by a rat liver preparation, the appearance of a yellow color similar to that of pyridoxal 5-phosphate was observed in the samples containing pyridoxamine 5-phosphate. Further investigation has revealed the presence of a soluble enzyme system in extracts of several mammalian tissues which catalyzes the oxidation of PAMP’ to PALP according to the following equation z2
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Burton M. Pogell (1958) studied this question.
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