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A Bence Jones protein (BJ Juv) with a rather unusal N‐terminal amino acid sequence has been found. An antiserum specific for this protein was developed and used to screen normal sera, M‐component sera, Bence Jones protein containing urines, and isolated kappa chains. Out of the sera tested only 2 of the 66 macroglobulinemia sera reacted strongly. N‐terminal sequence analysis of the isolated kappa chains showed that the amino acid sequence was nearly identical with that found for BJ Juv and that of the V K IV subgroup.
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Sletten et al. (1974) studied this question.
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