Answers are grounded in this paper and cite their sources.
We report here a novel synthesis of optically active bishomotyrosine. The bishomotyrosine skeleton was constructed by using a Friedel-Crafts reaction between phenol and optically active N-Tfa-Glu(Cl)-OMe in triflic acid under the mild condition. Reduction and subsequent deprotection then afforded bishomotyrosine derivatives without any loss of optical purity.
No takes yet. Share an insight, caveat, or question.
Murai et al. (2011) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: