The application of integrated circuit technology to the field of physiological data acquisition may produce a significant impact on patient monitoring, diagnosis and therapeutic medical decisions. Biomedical sensors based on IC technology have several potential advantages not available in present biomedical sensors. These include small size, reliability, rapid time response, multi-sensor chip, and onchip signal processing to achieve high to low impedance transformation, temperature compensation, signal multiplexing, etc.
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Moss et al. (1978) studied this question.
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