2-alkynyl buta-1,3-dienes 4 can be synthesized in moderate to high yields by the reactions of the corresponding diiodides 1 derived from methylenecyclopropanes with substituted alkynes 2 via Sonogashira cross-coupling in the catalysis of Pd(PPh3)4/CuI.
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Shao et al. (2005) studied this question.
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