This case highlights the unpredictable behavior of renal cell carcinoma, including the rare phenomenon of spontaneous regression of metastases and tumor thrombus necrosis.
Spontaneous RCC regression remains unpredictable; this case extends rare reports of metastasis and thrombus necrosis without therapy but leaves mechanisms and frequency open.
Idiopathic regression of metastases is one of the features of the unpredictable behaviour of renal cell carcinoma. We report a patient with pulmonary metastases and a tumor thrombus in the inferior vena cava with spontaneous regression of the lung lesions and necrosis of the thrombus before any therapy was instituted.
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Bos et al. (1996) studied this question.
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