A previous investigation of the effect of roentgen irradiation on the brain in rabbits showed that vestibulo-cerebellar signs were very common (BERG and LINDGREN 1958).This has prompted an analysis of the dose factors and the morphology and site of lesions after roentgen irradiation in single doses as well as fractionated doses to one half of the head of the rabbit.This forms the subject of the present communication.Labyrinthine sigm not verijied histologically.The effect of ionizing radiation on the ear was demonstrated as early as in 1905 by EWALD.A glass ball containing about 3 mg radium bromide placed in the region of the labyrinth for some hours (the species of animal used was not mentioned) produced after some days signs that were of the same type as those occurring after extirpation of the labyrinth, such as turning of the head.The severity of the signs varied with the irradiation time.HALBERSTADTER (1920) reported that after mice had been submitted to protracted roentgen irradiation of one side of the skull they ran around in circles with the irradiated side innermost; the animals died a few hours later (cit. THIELEMANN).
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Berg et al. (1961) studied this question.