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January 1, 1996Chemical Communications

Selective fluorination of β-ketoesters using iodotoluene difluoride and a HF–amine complex

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Abstract

β-Ketoesters are selectively fluorinated at the α-position by iodotoluene difluoride and a HF–pyridine complex.

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Cite This Study

Hara et al. (1996) studied this question.

synapsesocial.com/papers/6a85ad9a4fe931a6e65e2fa8 https://doi.org/10.1039/cc9960001899

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Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

1Substituent effects in the fluorination-rearrangement of 1,1-diarylethenes with aryliodine(III) difluoridesOriginal Research · 1980 · 55 citations
2Room temperature fluorination of 1,3-diketones and enol acetates with xenon difluorideOriginal Research · 1980 · 23 citations
3Fluorination with xenon difluoride. 27. The effect of catalyst on fluorination of 1,3-diketones and enol acetatesOriginal Research · 1982 · 53 citations