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In normal subjects a marked diurnal variation was disclosed in the concentrations of immunoglobulin G (IgG), IgA and albumin in nasal secretion, the night values being 4.5-5.5 times higher than those during the day. It is suggested that this is due to changing secretory activity of the nasal glands.
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Mygind et al. (1976) studied this question.
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