The extravasation of endogeneous rat albumin and exogeneous 125I-labeled human serum albumin was compared in rats subjected to bicuculline-induced blood-brain barrier dysfunction. The correlation between rocket immunoelectrophoretic assays of endogeneous rat albumin and 125I-labeled human serum albumin, assayed by gamma scintillation counting, was good respective of whether 125I-labeled albumin was studies in whole brain tissue or in brain homogenates. The ratio of brain to serum albumin was similar with the two assay methods.
No takes yet. Share an insight, caveat, or question.
Persson et al. (2009) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: