The wide range of application of 2,6‐di‐ O ‐methyl‐3‐ O ‐pentyl‐β‐and y ‐cyclodextrins is demonstrated by the resolution of the enantiomers of the methyl esters of chiral carboxylic acids: α and β hydroxy acids with up to 18 carbon atoms, hydroxy di‐ and tricarboxylic acids, and alkyl/aryl‐substituted carboxylic acid methyl esters, including the plant hormone abscisic acid, insect juvenile hormones, and some non‐steroidal anti‐inflammatory drugs can be resolved with generally large separation factors. The new cyclodextrin derivatives also exhibit high selectivity for epoxides.
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König et al. (1993) studied this question.
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