Why the study?
Evaluating fine particulate matter (PM2.5) health effects within single-exposure frameworks limits causal inference and reduces the translational relevance of evidence for policy development.
Design
Review
Key result
Reconceptualizing PM2.5 within the exposome framework highlights the limitations of single-exposure assessments and supports integrative approaches for evaluating cumulative health risks.
Authors
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Integrating PM2.5 into exposome models may improve causal inference; leaves open translation to clinical or policy recommendations.
Positioning PM2.5 as a sentinel indicator of cumulative environmental risk provides a unifying framework for exposome-informed science and supports the development of more precise, equitable, and policy-relevant interventions.
Sangkham et al. (2026) conducted a review in PM2.5 exposure and cumulative health risk. Fine Particulate Matter (PM2.5) was evaluated. Reconceptualizing PM2.5 within the exposome framework highlights the limitations of single-exposure assessments and supports integrative approaches for evaluating cumulative health risks.
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