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November 1, 2010Cellular and Molecular NeurobiologyOpen Access

Regulatory Peptides from Chromogranin A and Secretogranin II

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Abstract

This commentary is focusing on novel aspects on the secreted CgA- and SgII-derived peptides, vasostatin-I (bovine and human CgA(1-76), VS-I), WE-14 (CgA(316-329)), catestatin (bovine CgA(344-366), human CgA(352-372), Cts) and the SgII-derived secretoneurin (SgII(180-204)) as significant regulators of inflammatory reactions.

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Karen B. Helle (2010) studied this question.

synapsesocial.com/papers/6a85bb70afd961f1253dbad1 https://doi.org/10.1007/s10571-010-9552-6

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1The Release of Protein from the Stimulated Adrenal MedullaIn Vitro Study · 1965 · 275 citations
2Secretoneurin: A New Player in Angiogenesis and Chemotaxis Linking Nerves, Blood Vessels and the Immune SystemOriginal Research · 2005 · 90 citations
3The chromogranin A-derived peptides vasostatin-I and catestatin as regulatory peptides for cardiovascular functionsReview · 2009 · 74 citations
4Catestatin is a novel endogenous peptide that regulates cardiac function and blood pressureOriginal Research · 2008 · 78 citations
5Catestatin Improves Post-Ischemic Left Ventricular Function and Decreases Ischemia/Reperfusion Injury in HeartIn Vitro Study · 2010 · 74 citations

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