ETIOLOGY AND HISTOLOGY Many papillomas spring from an inflammatory, syphilitic, tuberculous or even a malignant base, and histologically the malignant are but an exaggerated and continued form of the benign papilloma. A beginning hyperplasia on the vocal cord, irrespective of its underlying cause, may in due course of time assume proportions, varying from a small papular mound to a mass of epithelial growth filling the entire larynx. The proliferation in all cases is chiefly that of the epithelium, although there will be found fibrous thickenings occupying largely the posterior laryngeal wall and the posterior half of the vocal cords, which are seen quite frequently in habitual consumers of alcoholic beverages, also in newsboys, peddlers, hawkers and in those suffering from chronic or atrophic rhinitis. In singers, particularly those with soprano or tenor voices, these thickenings of the epithelium occur on the anterior third of the cord, and are the result
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Harmon Smith (1914) studied this question.