Why the study?
Does RRAD reduction improve systolic function in models of dilated cardiomyopathy?
Does RRAD reduction improve systolic function in models of dilated cardiomyopathy?
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Targeting RRAD to modulate L-type calcium channels improves contractility and reverses remodeling in a mouse model of dilated cardiomyopathy, offering a potential new approach for precision inotropes without pro-arrhythmic effects.
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Obeidat et al. (2025) conducted an editorial in Heart failure with reduced ejection fraction. RRAD reduction was evaluated on Fractional shortening.
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