The Role of Anemia of Inflammation in the Course of Chronic HBV Infection in Children

The article evaluates the features of the course of chronic HBV infection in children with the background of anemia of inflammation. A brief description of the clinical and laboratory manifestations of the disease is given, depending on the course of anemia and inflammation. The data on hepcidin dynamics are analyzed. The stage–by-stage formation of iron metabolism disorders was revealed, in the form of a true deficiency with a breakdown of ferrokinetic markers – an increase in hepcidin and soluble transferin receptors with the background reduced ferritin values characteristic of iron deficiency anemia in the initial stages of the disease and, redistributive iron deficiency - decrease in hepcidin and soluble transferrin receptors with the background increased ferritin values characteristic of iron overload the body is in the late stages of the disease.