Surface‐enhanced Raman scattering (SERS) spectra of vitamin B complex extracted in ethanol were analyzed using a silver‐coated alumina substrate. The SERS effect appears to enhance selectively the spectrum of p ‐aminobenzoic acid (PABA) from among the complex constituents of the vitamin B complex tablet. A calibration graph of SERS signal intensity versus concentration of PABA was constructed for quantitative analysis. With such a graph it is possible to detect PABA down to low parts per million levels. The potential of the SERS technique in other analytical and biomedical areas is discussed.
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Narayanan et al. (1991) studied this question.
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