Vitamin D Supplementation Associated With Alterations in Lipid Metabolism in Children With Glomerular Disease

Low levels of vitamin D are predictive of many adverse health outcomes. However, trials of vitamin D supplementation in adults, while successfully increasing vitamin D levels, have failed to show any benefit on cardiovascular, stroke, or bone health outcomes.1,2 Vitamin D supplementation in children and adolescents has similarly shown no improvement in cardiometabolic or body composition/growth outcomes.3 Whether there are metabolic effects associated with vitamin D supplementation that may attenuate other potential health benefits is uncertain.