Why the study?
Increasing academic efforts have explored the link between long noncoding RNAs and metabolic diseases, prompting a review of the functions and mechanisms of lncRNA H19 in diabetes mellitus and diabetic complications.
LncRNA H19 serves as a potential instructive marker and therapeutic target for diabetes mellitus and its complications.
Does not support clinical adoption in diabetes; leaves open prospective validation as a marker.
BACKGROUND: Increasing academic efforts have been made to explore the correlation of long noncoding RNAs (lncRNAs) with human diseases, particularly metabolic diseases like diabetes mellitus. Taking lncRNA H19 as an example, this review intends to reveal the functions and mechanism of lncRNA H19 in diabetes mellitus and diabetic complications. METHODS: The research results associated with lncRNA H19 and diabetes mellitus are collected and summarized on PubMed. CONCLUSION: LncRNA H19 is a potential instructive marker for the treatment of diabetes mellitus and diabetic complications.
No takes yet. Share an insight, caveat, or question.
Zhu et al. (2021) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: