Thrombocytopenia and Extragonadal Germ-Cell Neoplasm

Letters and Corrections1 August 1984Thrombocytopenia and Extragonadal Germ-Cell NeoplasmLEE J. HELMAN, M.D., ROBERT F. OZOLS, M.D., PH.D., DAN L. LONGO, M.D.LEE J. HELMAN, M.D.Search for more papers by this author, ROBERT F. OZOLS, M.D., PH.D.Search for more papers by this author, DAN L. LONGO, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-101-2-280 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: A report by Garnick and colleagues (1) has described three cases of idiopathic thrombocytopenia associated with extragonadal germ-cell tumors. We report an additional case in which idiopathic thrombocytopenia was associated with an extragonadal germ-cell neoplasm.A 24-year-old man presented with superior vena cava obstruction and had a large anterior superior mediastinal mass. A biopsy specimen of the mass showed an endodermal sinus tumor and embryonal carcinoma. There was no evidence of testicular, retroperitoneal, or bone marrow involvement. Multiple hepatic metastases were found. The initial serum alpha-fetoprotein level was 5400 ng/mL, and peripheral blood count before therapy showed...References1. GARNICK M and GRIFFIN J. Idiopathic thrombocytopenia in association with extragonadal germ cell cancer. Ann Intern Med. 1983;98:926-7. LinkGoogle Scholar2. BELLONE J, KUNICKI T, and ASTER R. Immune thrombocytopenia associated with carcinoma. Ann Intern Med. 1983;99:470-2. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: LEE J. HELMAN, M.D.; ROBERT F. OZOLS, M.D., PH.D.; DAN L. LONGO, M.D. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byProtocol for the Examination of Specimens From Pediatric and Adult Patients With Extragonadal Germ Cell TumorsDevelopment of Acute Megakaryoblastic Leukemia with Isochromosome (12p) after a Primary Mediastinal Germ Cell Tumor in KoreaA rare case of idiopathic thrombocytopenia in association with an ovarian teratoma in pregnancyConcurrent mediastinal germ-cell tumour and haematological malignancy: Case report and short review of literatureExtragonadal Germ Cell Tumors: A Review With Emphasis on Pathologic Features, Clinical Prognostic Variables, and Differential Diagnostic ConsiderationsIdiopathic thrombocytopenia associated with dysgerminoma in a patient with androgen insensitivity syndromeDiagnosis, staging, and clinical characteristics of the patient with mediastinal germ cell carcinomaMediastinal Immature Teratoma with Yolk Sac Tumor and MyelomonocyticLeukemia Associated with Klinefelter's SyndromeGerm Cell Neoplasms and Other Malignancies of the MediastinumMediastinal Non-seminomatous Germ Cell Tumours: Their Association with Non-germ Cell MalignanciesCase 40-1997Systemic mast cell disease associated with primary mediastinal germ cell tumorSystemic mast cell disease associated with primary mediastinal germ cell tumorMalignant Hematologic Disorders Arising from Mediastinal Germ Cell Tumors. A Review of Clinical and Biologic FeaturesHematologic Neoplasia Associated with Primary Mediastinal Germ-Cell TumorsMediastinal germ cell tumour associated with malignant histiocytosis and high rubella titresHematologic Malignancies Associated with Primary Mediastinal Germ-Cell TumorsCRAIG R. NICHOLS, M.D., RONALD HOFFMAN, M.D., LAWRENCE H. EINHORN, M.D., STEPHEN D. WILLIAMS, M.D., LAWRENCE A. WHEELER, M.D., MARC B. GARNICK, M.D. 1 August 1984Volume 101, Issue 2Page: 280-280KeywordsBiopsyBlood countsBone marrow ePublished: 1 December 2008 Issue Published: 1 August 1984 PDF downloadLoading ...