Differential Diagnosis of Terminal Glomerulonephritis and Malignant Hypertension. I. Renal Aspects

Article1 November 1944DIFFERENTIAL DIAGNOSIS OF TERMINAL GLOMERULONEPHRITIS AND MALIGNANT HYPERTENSION. I. RENAL ASPECTSA. C. CORCORAN, M.D., IRVINE H. PAGE, M.D., F.A.C.P.A. C. CORCORAN, M.D.Search for more papers by this author, IRVINE H. PAGE, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-21-5-747 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptDifferential diagnosis in patients showing severe renal damage from chronic glomerulonephritis on the one hand, and malignant hypertension on the other has always been difficult. At this stage the two conditions have in common the clinical pattern of hypertension, loss of weight, anemia, so-called "albuminuric retinitis," depressed renal function, azotemia, proteinuria and increased organized urinary sediment. Indeed, at least cases 1 and 8 of Bright's original report and cases 1, 5 and 8 of his second paper in Osman's edition1seem to us instances of hypertension, essential or malignant rather than the characteristic syndrome, glomerulonephritis, which now most characteristically bears...Bibliography1. OSMAN AA Original Papers of RICHARD BRIGHT on Renal Disease., 1937. Oxford University Press, London. Humphrey Milford. 1937. Google Scholar2. SMITHGOLDRINGCHASIS HWWH: The measurement of the tubular excretory mass, effective blood flow and filtration rate in the normal human kidney, Jr. Clin. Invest., 1938, xvii, 263. CrossrefGoogle Scholar3. CORCORANPAGE ACIH: Applications of diphenylamine in the determination of levulose in biological mediums. I. The determination of inulin, Jr. Biol. Chem., 1939, cxxvii, 601. CrossrefGoogle Scholar4. CORCORANPAGE ACIH: The determination of diodrast-iodine in blood and urine, Jr. Lab. and Clin. Med., 1943, xxviii, 1514. Google Scholar5. 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